Dr. Tien Ng from the University of Southern California moderated the topic "Current and Future Strategies for Overcoming Diuretic Resistance in Acute Heart Failure," with Drs. Mandeep Mehra from the Brigham and Women's Hospital and Harvard Medical School and Jo Ellen Rodgers from the University of North Carolina.
The discussion focused primarily on:
(1) the role of continuous infusion and high versus low dose loop diuretics to overcome diuretic resistance;
(2) additional agents that augment the diuretic effect while having a loop diuretic sparing effect; and
(3) optimal endpoints, and right-sided failure and its cotribution to the cardiorenal syndrome.