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Date: June 28, 2010Roundtable ID: CV0024Citation: Med Roundtable Cardiovasc Ed. ; 1(3): 182 - 189.
Pharmacological Therapy for Regurgitant Valve Lesions: Does It Really Work?
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Discussants:
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Summary:
Dr. Jeffrey Borer from the SUNY Downstate Medical Center moderated the topic "Medical Therapy for Regurgitant Valve Lesions: Do They Really Work?" with Drs. Blase Carabello from the Michael E. DeBakey VA Medical Center and Dr. Mark Starling from Banner Heart Hospital participating.
- The discussion focused primarily on:
- (1) potential effects of pharmacological unloading therapy in aortic and mitral regurgitation,
- (2) the differences in potential effects in these two diseases,
- (3) clinical trial data available to support conclusions,
- (4) potential utility of vasodilating and other heart failure therapy prior to planned surgery for patients with regurgitant valve disease and heart failure,
- (5) potential importance of adverse actions of specific vasodilators that could compromise theoretical benefits,
- (6) potential roles of drug therapies for problems other than volume overload that may be associated with regurgitant valve diseases, including prophylaxis for infective endocarditis, among others.
- (Med Roundtable Cardiovasc Ed. 2010;1(3):182-189) ©2010 FoxP2 Media, LLC
*Dr. Starling was unable to attend the live discussion and subsequently inserted his commentaries.
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Compounds:Trials:
Evangelista Study, SHIFT Study
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