I am Professor of Medicine at Columbia University Medical Center, Director of Cardiovascular Research and Education at the Center for Interventional Vascular Therapy at New York Presbyterian Hospital in New York City, Co-Director of Medical Research and Education at the Cardiovascular Foundation, and a practicing interventional cardiologist.
I have served as principal investigator, study chairman or on the executive committee for more than 60 national or international trials investigating optimal therapies (drugs and devices) for patients with coronary artery disease. In this capacity I designed the trials, was involved in their regulatory submission and all aspects of implementation, data analysis, and prepared the primary manuscript for each study. This work has served as the basis for regulatory approval of numerous devices in the United States, and has informed the guidelines in multiple areas. My specific areas of research have focused on therapies of acute coronary syndromes and myocardial infarction; stable ischemic heart disease; drug eluting stents; adjunct pharmacology; percutaneous heart valves, new device angioplasty including distal embolic protection, thrombectomy, vascular brachytherapy and stent grafts; intravascular ultrasound imaging; saphenous vein graft therapies; chronic total occlusions; vulnerable plaque; contrast nephropathy; and clinical trial design; and regulatory issues.
I have authored more than 1000 book chapters, manuscripts and abstracts published in the peer-reviewed literature, and have delivered thousands of invited lectures around the world on these subjects. I am the director of Transcatheter Cardiovascular Therapeutics (TCT), the world's largest symposium devoted to interventional cardiology and vascular medicine, direct the annual National Interventional Cardiology Fellow's Course, and co-direct several other annual courses, including Complex PCI: A Vision for the Future, The Chronic Total Occlusion and Left Main Summit, and Transcatheter Valve Therapies.