H. Bryan Brewer, Jr, MD, is Director of Lipoprotein and Atherosclerosis Research at the Cardiovascular Research Institute, MedStar Research Institute, Washington Hospital Center, Washington, DC. Until 2005, he was Chief of the Molecular Disease Branch at the National Heart, Lung, and Blood Institute, National Institutes of Health, in Bethesda, Maryland, where he worked for 29 years. He is also Chief Scientific Director of Lipid Sciences (Pleasanton, California). Dr. Brewer is a member of the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP).
Dr. Brewer's research led to the first published sequences for the human plasma apolipoproteins; the initial determination of the metabolism of the plasma apolipoproteins in normal and hyperlipidemic individuals; as well as the identification of multiple gene defects leading to the genetic dyslipoproteinemias. More recently, Dr. Brewer has pioneered the use of transgenic mice and rabbits as well as recombinant adenovirus vectors to identify genes that modulate lipoprotein metabolism and the development of atherosclerosis.
Dr. Brewer has published more than 400 original reports and 70 reviews and book chapters on the subjects of genetic dyslipoproteinemias, lipoprotein metabolism, and atherosclerosis.